Identify Protein that Contributes to the Neurotoxicity in Alzheimer's Disease

Anitha SP 1 , Jahnavi. R2 , Bhargavi P3

NIJ. 2021 February; 2(1): 11–15. Published online 2021 February

Abstract : Thinking ability of the brain is affected and this kind of mental health issue is known as Alzheimer's. The entire study is conducted with the causes and effects of Alzheimer's. The proteins which are involved in Alzheimer's have been discussed in this whole study. Amyloid and tau are the proteins which have huge influence have been described in the proposed study. Abnormal protein formation is built by BCAA that is known as the transportation system of amino acids. Abnormal formation of protein damages the building of tissue in the neighbourhood tissue of the brain and for this formation capabilities of the brain is badly affected. Many people are facing the issues of low thinking ability and Alzheimer's is responsible for these issues. Tau is another protein which is produced by alternative splicing. This protein is abundant in neurons that are part of the Central nerve system. Various chemicals are produced through the abundance of tau protein. Both secondary qualitative and quantitative analysis have been in the study to identify the proteins which have huge impact for the cause of Alzheimer's..

Keywords : Alzheimer's, neurotransmitter, neurotoxicity, Protein.

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